NASDAQ
$143.79
$143.79

Overview

Price performance
Low
$138.62
High
$145.61
Market open. Last updated: Nov 4, 2026, 7:07 PM UTC
$
143.79
3.55 (2.53%)
Average, 50 days
$142.34
$117.19
Open
$145.61
Previous close
$140.24
52-week high
$160.81
Aug 19, 2026 (3 months ago)
52-week low
$75.55
Nov 5, 2025 (13 months ago)
90.32%

Valuation & Estimates

Earnings

Financials

Insider Trading

Peer Analysis

Insights & Activity

Market Cap
9.30B
Volume
228 121
Total Return (3M)
5.78%
Total Return (1Y)
87.78%
19.34
Sector
Healthcare
Links
Tags
Healthcare
Biotechnology
NASDAQ
US
Socials
About
Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of polycythemia vera, hereditary hemochromatosis, and other blood-related ailments. Also in Phase II development is PN-943, an oral peptide engineered as a specific antagonist of alpha-4-beta-7 integrin, intended for addressing inflammatory bowel disease (IBD). Furthermore, they are progressing PN-235, an orally administered antagonist specifically targeting the interleukin-23 receptor, designed for both IBD and various non-IBD therapeutic applications. Protagonist Therapeutics maintains a licensing and collaborative agreement with Janssen Biotech, Inc. Founded in 2006, the company's headquarters are located in Newark, California.