News
IQIRVO® late-breaking data raises ambitions in PBC with more than 85% of patients on treatment achieving ALP normalization
Nov 5, 11:30 AM·
High Optimistic

Sources

Summarized by i88

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Summary

Late-breaking ELSPIRE data presented at The Liver Meeting 2026 and published in HEPATOLOGY show 85.3% of IQIRVO-treated patients achieved ALP normalization at Week 52 in primary biliary cholangitis, versus 23% in the comparator arm. The results support broader positioning for IQIRVO in PBC; no ticker was specified in the release.

Late-breaking results from the ELSPIRE study show that 85.3% of patients receiving IQIRVO achieved normalization of ALP at Week 52, compared with 23% in the comparator arm, according to the source release.

Presentation and publication

The ELSPIRE results will be presented as late-breaking data at The Liver Meeting 2026 and simultaneously published in HEPATOLOGY, described in the release as AASLD’s flagship journal.

Key data point

  • At Week 52, 85.3% of patients receiving IQIRVO achieved normalization of ALP.
  • The comparator arm recorded 23%.

Context

The release frames the data as raising ambitions in PBC (primary biliary cholangitis). No ticker was specified in the release.